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名称：BIOSILK
用途：A 3D Culture Environment for Expansion and Differentiation of Human PSCs.
货号：BS-0101
保存温度：-80℃
BIOSILK IS A BIOMATERIAL MADE FROM RECOMBINANT SPIDER SILK PROTEIN FOR 3D CELL CULTURE. THE BIOSILK SOLUTION MAY ADVANTAGEOUSLY BE FUNCTIONALIZED WITH THE BIOLAMININ PRODUCT OF CHOICE, FOR IMPROVED CELL FUNCTIONALITY.
A BIOMATERIAL DESIGNED FOR 3D CELL CULTURE OF HUMAN PLURIPOTENT STEM CELLS
BIOSILK IS A BIOMATERIAL MADE FROM RECOMBINANT SPIDER SILK PROTEIN FOR 3D CELL CULTURE. THE BIOSILK SOLUTION MAY ADVANTAGEOUSLY BE FUNCTIONALIZED WITH THE BIOLAMININ PRODUCT OF CHOICE, FOR IMPROVED CELL FUNCTIONALITY. BIOSILK IS IDEAL FOR INTEGRATION, PROLIFERATION AND SUBSEQUENT LINEAGE-SPECIFIC DIFFERENTIATION OF HUMAN PLURIPOTENT STEM CELLS IN A 3D FORMAT.
Biosilk is a biocompatible, biodegradable and non-immunogenic biomaterial, which facilitates the use in clinical applications. The extendable Biosilk macrofibre material can self-assemble into several formats; foams, fiber bundles, and thin films.
A MORE BIOLOGICALLY RELEVANT CULTURE ENVIRONMENT
Compared to 2D cultures, a 3D culture is a more biologically relevant culture environment with a higher degree of architectural complexity that retains homeostasis for longer.
Contrary to many other 3D scaffolds, the cells can be added to the Biosilk solution before the network stabilizes, resulting in a uniform integration of the cells between the microfibers. Unlike cells cultured in a hydrogel, cells seeded in the Biosilk scaffold attach along the microfibers and are in contact with other cells like in tissue. Moreover, the cells proliferate more efficiently and migrate in the Biosilk scaffold and have full and even access to both the medium, matrix, and neighboring cells, compared to when encapsulated in a hydrogel.
FEATURES AND SPECIFICATIONS:
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Flexible 30 culture system that can be assembled into different formats
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Elastic microfibers mimicking the ECM
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Biocompatible
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Biodegradable
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Non-immunogenic
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Defined and animal origin-free to the primary level
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For research use only
BIOSILK 521 FOAM MORPHOLOGY
Representative pictures of the Biosilk 521 foam taken from above day 0, 1 and 3 after cell seeding. The initial small bubbles merge into bigger bubbles that disperse after a few days, resulting in a 3D scaffold with integrated cells.
Order Information
| Product Name | Cat. No. | Size | Description |
| BIOSILK | BS-0101 | 750 µg（1 x 250 µL） | Recombinant spider silk protein for 3D culture applications |
Technical Resources
