品名:cGMP 重组人白介素12
货号:AK9995
描述:Akron cGMP Recombinant Human Interleukin-12, rHu IL-12, cGMP IL12
Akron cGMP IL-12 Documents
Safety Data Sheet (SDS)
Product Page
Akron cGMP IL-12 Description
人白细胞介素12(IL-12,白介素12)是一由p35和p40(IL-12β)两条链组成的异源二聚体,两个亚单位通过二硫键连接在一起。IL-12受体主要由活化的T细胞、NK细胞、DC细胞和B细胞表达。
描述:Interleukin-12 (IL-12) was identified as a factor secreted by human Epstein-Barr (EBV)-transformed B cell lines. IL-12 is produced predominantly by monocytes and NK cells. Human IL-12 is not active on mouse cells, but murine IL-12 is active on both murine and human lymphocytes.
Akron cGMP IL-12 Specification
Source: CHO
Size: 40μg, 1mg
Molecular weight: 75 kDa
Akron cGMP IL-12 Application
Akron cGMP IL-12 重组人白细胞介素12可用于细胞治疗。
The biological activity of recombinant human IL-12 was measured by its ability to stimulate the proliferation of PHA-activated human T lymphoblasts. IL-12 has anti-angiogenic properties. Recombinant Human Interleukin-12, produced in CHO, is a glycosylated disulfide linked heterodimeric polypeptide that contains 503 amino acids and has a molecular weight of 75 kDa. It is comprised of disulfide-bonded 35 kDa (p35) and 40 kDa (p40) subunits. rHu IL-12 is purified by proprietary chromatographic techniques.
Lyophilized (20 μg) Cat. # AK9995-0020
Lyophilized (100 μg) Cat. # AK9995-0100
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